2. Signaling Pathways
  3. PROTAC
  4. E3 Ligase Ligand-Linker Conjugates
  5. E3 Ligase Ligand-Linker Conjugates Ligand

E3 Ligase Ligand-Linker Conjugates Ligand

E3 Ligase Ligand-Linker Conjugates Isoform Comparison

E3 Ligase Ligand-Linker Conjugates Ligands (3):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-W854844A
    (E)-JP-2-196 TFA 3065021-33-9
    JP-2-196 (TFA) is a molecular glue handle that can bind to the E3-ubiquitin ligases (RNF126, LRSAM1, RNF40, MID2, and RNF14) in vitro. JP-2-196 (TFA) can be used to synthesize molecular glue degraders.
    (E)-JP-2-196 TFA
  • HY-179435
    (S,R,S)-AHPC-Bromooctanoic acid 2408342-03-8
    (S,R,S)-AHPC-Bromooctanoic acid is a conjugate of E3 ligase ligand and linker, consisting of (S,R,S)-AHPC (HY-125845) and the corresponding linker (HY-W007700). (S,R,S)-AHPC-Bromooctanoic acid can serve as VHL (von Hippel-Lindau) ligand to recruit the VHL protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
    (S,R,S)-AHPC-Bromooctanoic acid
  • HY-174474
    (S,R,S)-AHPC-Me-amide-C15-acid
    (S,R,S)-AHPC-Me-amide-C15-acid is a synthesized E3 ligase ligand-linker conjugate that can be used for synthesis of PROTACs such as C199 (HY-174445).
    (S,R,S)-AHPC-Me-amide-C15-acid